Clear Evidence of Carcinogenic Activity by a Whole-Leaf Extract of Aloe barbadensis Miller (Aloe vera) in F344/N Rats
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چکیده
منابع مشابه
Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis miller (aloe vera) in F344/N rats.
Aloe barbadensis Miller (Aloe vera) is an herbal remedy promoted to treat a variety of illnesses; however, only limited data are available on the safety of this dietary supplement. Drinking water exposure of F344/N rats and B6C3F1 mice to an Aloe vera whole-leaf extract (1, 2, and 3%) for 13 weeks resulted in goblet cell hyperplasia of the large intestine in both species. Based upon this observ...
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Aloe vera has been used worldwide both for pharmaceutical, food, and cosmetic industries due to the plethora of biological activities of some of its metabolites. The aim of this study was to evaluate the antifungal and antioxidant activities of the leaf extract. The antifungal activity was determined by the agar-well diffusion method against plant and human fungal pathogens. The methanol and et...
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BACKGROUND: Aloe vera, a succulent plant prevalent in hot, dry regions of Asia, Africa, and other areas, has been used in traditional medicine for many centuries. It is easily propagated in most places where the climate is hot and dry. The gel and dried latex obtained from aloe leaves are used for relief of constipation; for wound healing; and for treatment of burns, psoriasis, frostbite, ulcer...
متن کاملChemical Composition and Biochemical Activity of Aloe vera (Aloe barbadensis Miller) Leaves
Aloe.vera has a long history as a medicinal plant with diverse therapeutic applications. This study was conducted to determine chemical composition and biochemical activity of A. vera leaves. Proximate composition (moisture, ash, crude protein, crude lipid and crude fibre), ascorbic acid, superoxide dismutase, catalase, peroxidase, amylase, reducing sugars and total soluble sugars were determin...
متن کاملStructural Modifications of Fructans in Aloe barbadensis Miller (Aloe Vera) Grown under Water Stress
Aloe barbadensis Miller (Aloe vera) has a Crassulaceae acid metabolism which grants the plant great tolerance to water restrictions. Carbohydrates such as acemannans and fructans are among the molecules responsible for tolerating water deficit in other plant species. Nevertheless, fructans, which are prebiotic compounds, have not been described nor studied in Aloe vera, whose leaf gel is known ...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2012
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfs275